Research Notes
Blog
Mechanism breakdowns, trial data analysis, and protocol guides. No opinion pieces — only data.
Retatrutide vs Tirzepatide: Which Has Better Fat Loss Data?
Phase 2 vs Phase 3 trial data: −28.7% versus −20.9% body weight reduction. The glucagon receptor explains the difference.
BPC-157: What 140 Preclinical Studies Actually Show
140+ indexed preclinical studies, six distinct mechanisms, zero human RCTs. A rigorous review of what the BPC-157 evidence base actually contains.
The Looksmaxxing Peptide Stack: GHK-Cu, SNAP-8, and Melanotan II
Three compounds, three distinct mechanisms: collagen upregulation, SNARE-mediated expression line reduction, and MC1R melanogenesis. Research basis explained.
GHK-Cu: 4,000 Genes and What They Mean for Skin Research
The Broad Institute genomic dataset, +70% collagen I in fibroblast models, and the plasma decline curve placing GHK-Cu at the centre of anti-aging research.
Epithalon: 50 Years of Telomerase Research From St. Petersburg
Khavinson tetrapeptide: telomerase activation in cell culture, melatonin restoration, and rodent lifespan extension data — a critical literature review.
How to Reconstitute Peptides: The Complete Research Protocol
BAC water ratios, concentration tables, freeze-thaw stability, and step-by-step technique — the complete technical protocol for peptide reconstitution.